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September 1, 2011Journal of Biomechanical EngineeringOpen Access

Near Valve Flows and Potential Blood Damage During Closure of a Bileaflet Mechanical Heart Valve

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Population

In vitro model of a bileaflet mechanical heart valve

Design

Preclinical

Authors

LHLuke H. HerbertsonSDSteven DeutschKMKeefe B. Manning

Discussion

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Overview

High shear during mechanical valve closure may promote thrombosis; leaves open valve design refinements and clinical validation.

Structured PICO

P
Population
In vitro model of a bileaflet mechanical heart valve
I
Intervention
Laser Doppler velocimetry and particle image velocimetry during the closing phase
O
Outcome
Near valve fluid velocities and stressessurrogate

In vitro analysis of bileaflet mechanical heart valves reveals that the closing phase generates high fluid stresses and shear rates, which may contribute to blood damage and thrombosis.

Cite This Study

Herbertson et al. (2011) studied this question.

synapsesocial.com/papers/6a7df9142d182a3d7e99b070https://doi.org/10.1115/1.4005167
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Simulation of the Three-Dimensional Hinge Flow Fields of a Bileaflet Mechanical Heart Valve Under Aortic Conditions2009 · 53 citations
  2. 2Relative Blood Damage in the Three Phases of a Prosthetic Heart Valve Flow Cycle1993 · 64 citations
  3. 3Modifying a Tilting Disk Mechanical Heart Valve Design to Improve Closing Dynamics2008 · 5 citations
  4. 4Cavitation Dynamics of Medtronic Hall Mechanical Heart Valve Prosthesis: Fluid Squeezing Effect1996 · 42 citations
  5. 5In Vivo Observation of Cavitation on Prosthetic Heart Valves1996 · 42 citations