February 1, 1974Journal of HygieneOpen Access

Swine vesicular disease: virological studies of experimental infections produced by the England/72 virus

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Population

Large white pigs ranging in weight from 30-40 kg

Design

Preclinical

Follow-up

Up to 5 weeks

Authors

RBR. BurrowsThe Pirbright Institute JMJ. A. MannThe Pirbright Institute DGDonna GoodridgeUniversity of Saskatchewan

Discussion

Member takes

Implication

Indicates early environmental contamination risk in swine; leaves open translation to field biosecurity or other vesicular diseases.

Structured PICO

Population

Large white pigs ranging in weight from 30-40 kg

Intervention

Exposure to England/72 swine vesicular disease virus via various routes (intradermal inoculation, skin scarification, oral/nasal instillation, or direct contact)

Outcome

Development of clinical disease and virus recovery from secretions, excretions, and tissuessurrogate

The study demonstrates that swine vesicular disease virus causes high levels of viral shedding following infection via skin or digestive tract mucosae, contributing to environmental contamination and disease spread.

Limitations

The response of pigs to graded amounts of virus was irregular and did not permit accurate determinations of the 50% infective doses
Results did not identify any particular region as the initial site of virus entry and multiplication

Cite This Study

Burrows et al. (1974) studied this question.

synapsesocial.com/papers/6a7dfda37c193befc433a7c6 https://doi.org/10.1017/s0022172400023305

View Full Paper

Ask AI

Bookmark

Swine vesicular disease: virological studies of experimental infections produced by the England/72 virus

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Swine vesicular disease: virological studies of experimental infections produced by the England/72 virus

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Also Consider

Also Consider