The skin is likely the most frequent route of infection for swine vesicular disease.
Supports targeted skin protection in swine handling; leaves open translation to natural outbreaks or other species.
The pathways of infection in swine vesicular disease have been studied by (i) an estimation of the amounts of virus required to produce infection by different artificial inoculation procedures; (ii) the distribution and amounts of virus in various tissues of pigs killed at intervals after contact infection; (iii) an investigation of the susceptibility to virus infection of pig tissue explants. The results show that pigs can be infected by a number of pathways and that the skin, as the most susceptible tissue, is probably the most frequent route of infection.
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Mann et al. (1980) studied this question.
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