Blood Pressure Excess for the Early Identification of Gestational Hypertension and Preeclampsia
Why the study?
Does the hyperbaric index derived from ambulatory blood pressure monitoring accurately predict the subsequent development of gestational hypertension or preeclampsia in pregnant women?
Population
152 pregnant women in the validation cohort, and a reference group of 189 normotensive pregnant women.
Design
Cohort
Follow-up
Throughout pregnancy (sampled every 4 weeks)
Authors
Discussion
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Member takes
Implication
May facilitate earlier gestational hypertension detection via ABPM; leaves open prospective validation and outcome impact.
Structured PICO
Does the hyperbaric index derived from ambulatory blood pressure monitoring accurately predict the subsequent development of gestational hypertension or preeclampsia in pregnant women?
P
Population
152 pregnant women in the validation cohort (92 with uncomplicated pregnancies and 60 who developed gestational hypertension or preeclampsia), and a reference group of 189 normotensive pregnant women.
I
Intervention
Determination of the hyperbaric index (area of blood pressure excess above the upper limit of the circadian 90% tolerance interval) via 48-hour ambulatory blood pressure monitoring performed once every 4 weeks.
O
Outcome
Early detection/diagnosis of subsequent gestational hypertension or preeclampsia.surrogate
The hyperbaric index calculated from ambulatory blood pressure monitoring provides a highly sensitive and predictive noninvasive method for identifying gestational hypertension and preeclampsia up to 23 weeks before clinical confirmation.
Limitations
- Inherent limitations of ambulatory blood pressure monitoring
Cite This Study
Hermida et al. (1998) studied this question.