Why the study?
Does low-dose aspirin and low-dose clonidine reduce acute kidney injury in patients undergoing non-cardiac surgery?
Does low-dose aspirin and low-dose clonidine reduce acute kidney injury in patients undergoing non-cardiac surgery?
This protocol describes the POISE-2 AKI substudy, which will determine if perioperative low-dose aspirin or clonidine impacts the incidence of acute kidney injury after non-cardiac surgery.
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POISE-2 AKI substudy results will guide perioperative AKI prevention strategies; leaves open whether low-dose aspirin or clonidine reduces incidence after non-cardiac surgery.
Garg et al. (2014) studied this question.
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