Why the study?
Does transcatheter aortic valve implantation improve clinical outcomes or cost-effectiveness compared to surgical aortic valve replacement in high-risk patients with aortic stenosis?
Population
7,906 high-risk patients with aortic stenosis pooled from 24 studies
Comparison
Transcatheter aortic valve implantation (TAVI) vs Conventional surgical aortic valve replacement
Design
Meta-analysis
Authors
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Supports TAVI as alternative to AVR in high-risk aortic stenosis; confirms major outcome equivalence across trials.
Does transcatheter aortic valve implantation improve clinical outcomes or cost-effectiveness compared to surgical aortic valve replacement in high-risk patients with aortic stenosis?
TAVI provides comparable short-term mortality and stroke outcomes to surgical AVR in high-risk aortic stenosis patients, though with differing procedural complication profiles.
Cao et al. (2016) studied this question.
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