The relationship between neutrophil percentage-to-albumin ratio and infarct related artery patency in patients with acute coronary syndrome

Alkame Akgümüş; Ali Duygu; Ahmet Balun

doi:10.32322/jhsm.1615413

March 21, 2025Journal of Health Sciences and MedicineOpen Access

The relationship between neutrophil percentage-to-albumin ratio and infarct related artery patency in patients with acute coronary syndrome

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Why the study?

Inflammation and low serum albumin are linked to prognosis in ACS, but the association of neutrophil percentage-to-albumin ratio with infarct-related coronary artery patency and MACE required investigation.

Does the neutrophil percentage-to-albumin ratio (NPAR) predict infarct-related artery patency and 365-day MACE in patients with acute coronary syndrome?

Structured PICO

Does the neutrophil percentage-to-albumin ratio (NPAR) predict infarct-related artery patency and 365-day MACE in patients with acute coronary syndrome?

P

Population

87 patients aged <65 years with acute coronary syndrome (ACS) who underwent coronary angiography, mean age 61.1, 74.7% male. Exclusions included active infectious disease, active carcinoma, hematologic proliferative diseases, chronic inflammatory disease, CABG, ACS and ischemic stroke in the last 3 months, active hepatobiliary diseases, steroid treatment, pulmonary embolism, pulmonary hypertension, and malignancy.

I

Intervention

Neutrophil percentage-to-albumin ratio (NPAR) calculated at admission

O

Outcome

Infarct-related coronary artery patency (IRA) at admission and major adverse cardiac events (MACE) at 365 days (composite of mortality due to reinfarction, stroke, malignant arrhythmia, and heart failure)composite

Limitations

Single-center design
Retrospective nature
Not all patients had albumin values, leading to a limitation in the number of patients
Age of the patients included was limited to <65 years

Implication

Higher neutrophil percentage-to-albumin ratio (NPAR) at admission is independently associated with non-patent infarct-related arteries and increased 1-year MACE in patients with acute coronary syndrome.

Discussion

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Cite This Study

Akgümüş et al. (2025) studied this question.

synapsesocial.com/papers/6a7e228e98f1ee41ab2569ef https://doi.org/10.32322/jhsm.1615413

View Full Paper

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The relationship between neutrophil percentage-to-albumin ratio and infarct related artery patency in patients with acute coronary syndrome

Structured PICO

Limitations

Implication

Discussion

Cite This Study

The relationship between neutrophil percentage-to-albumin ratio and infarct related artery patency in patients with acute coronary syndrome

Structured PICO

Limitations

Implication

Discussion

Cite This Study

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