Change of Serum Albumin and Risk of Cardiovascular Disease and All-Cause Mortality
Why the study?
Does a 3-year change in serum albumin concentration predict incident cardiovascular disease and all-cause mortality in older adults?
Population
713 respondents of the Longitudinal Aging Study Amsterdam initially aged 55-85 years.
Design
Cohort
Follow-up
6 years
Authors
Discussion
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Member takes
Implication
Declining albumin over 3 years was associated with higher incident CVD risk in older adults; leaves open its added value for risk stratification or monitoring.
Structured PICO
Does a 3-year change in serum albumin concentration predict incident cardiovascular disease and all-cause mortality in older adults?
P
Population
713 respondents of the Longitudinal Aging Study Amsterdam initially aged 55-85 years (n=456 for incident CVD analysis with no prevalent CVD at 3-year follow-up).
I
Intervention
3-year change in serum albumin concentration
O
Outcome
Incident cardiovascular disease (CVD) and all-cause mortality at 6-year follow-uphard clinical
A decrease in serum albumin concentration over 3 years in older adults is associated with an increased risk of incident cardiovascular disease, suggesting its potential as an early risk marker.
Cite This Study
Schalk et al. (2006) studied this question.