Towards 50 years of platelet function analyser (PFA) testing
Why the study?
Recommendations for platelet function analyser screening vary according to user experience as the PFA-100 approaches 50 years of age.
Design
Review
Authors
Discussion
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Member takes
Implication
May miss platelet defects on screening; leaves open need for prospective validation before routine use.
Structured PICO
I
Intervention
Platelet function analyser (PFA-100 and PFA-200) testing
The PFA-100 and PFA-200 are prevalent platelet function screening instruments with high sensitivity for von Willebrand disease and aspirin therapy, though clinical utility varies by user experience.
Cite This Study
Favaloro et al. (2022) studied this question.