December 28, 2011Circulation
Very Late Stent Thrombosis and Late Target Lesion Revascularization After Sirolimus-Eluting Stent Implantation
Why the study?
What is the long-term incidence and what are the risk factors for stent thrombosis and target lesion revascularization up to 5 years after sirolimus-eluting stent implantation?
Population
12,812 consecutive patients undergoing sirolimus-eluting stent (SES) implantation in the j-Cypher registry
Design
Cohort
Follow-up
5 years
Authors
Discussion
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Member takes
Implication
Continuous very late ST/TLR hazards after first-generation SES warrant surveillance; leaves open relevance to modern stents and optimal antithrombotic duration.
Structured PICO
What is the long-term incidence and what are the risk factors for stent thrombosis and target lesion revascularization up to 5 years after sirolimus-eluting stent implantation?
P
Population
12,812 consecutive patients undergoing sirolimus-eluting stent (SES) implantation in the j-Cypher registry
I
Intervention
Sirolimus-eluting stent (SES) implantation
O
Outcome
Cumulative incidence of definite stent thrombosis (ST) and target lesion revascularization at 5 yearshard clinical
Very late stent thrombosis and late target lesion revascularization remain continuous hazards up to 5 years after first-generation sirolimus-eluting stent implantation.
Cite This Study
Kimura et al. (2011) studied this question.