Why the study?
PAH remains a progressive disease with a poor prognosis requiring prompt therapy changes, highlighting the need for risk stratification methods to guide prognosis and treatment decisions.
Multiparametric risk stratification is a critical component of PAH management, guiding therapeutic decisions to achieve the guideline-recommended low-risk status.
May support risk-guided PAH decisions; leaves open prospective validation of tool impact on outcomes.
Despite significant advances in therapy, pulmonary arterial hypertension (PAH) remains a progressive disease with a poor prognosis. Immediately after establishing the diagnosis of PAH, urgent treatment with PAH-specific therapy is required. Due to the progressive nature of the disease, all patients should be closely monitored and their treatment regimen should be promptly changed according to clinical need. Risk stratification is an important method for informing the clinician and the patient about the prognosis of disease and the choice of therapy methods. The REVEAL scale and the ESC/ERS 2015 risk assessment table are important multifactorial tools for making decisions about the prescription and correction of PAH therapy, as well as for assessment of patients' response to therapy. Current guidelines for PAH indicate that the most important task of treatment of PAH is to achieve the low - risk status.
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Авдеев et al. (2019) studied this question.
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