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August 21, 2012Journal of Cardiovascular MedicineOpen Access

Rheumatic heart disease revisited

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Population

1,713 patients diagnosed with rheumatic heart disease at a large tertiary care hospital in eastern Nepal…

Design

Cohort

Authors

NSNikesh Raj ShresthaJamia HamdardThomas PilgrimThomas PilgrimInterventional / Structural CardiologyPKPrahlad KarkiB.P. Koirala Institute of Health Sciences

Discussion

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Implication

Sex differences in RHD lesions may inform screening awareness; leaves open need for prospective validation before practice change.

Structured PICO

P
Population
1,713 patients (1,055 female, 658 male) diagnosed with rheumatic heart disease (RHD) at a large tertiary care hospital in eastern Nepal, with 25.7% below 20 years of age.
O
Outcome
Patterns of valvular involvement assessed by transthoracic echocardiographysurrogate

In a large Nepalese cohort with rheumatic heart disease, mitral regurgitation is the most common lesion, with distinct sex differences in age of presentation and specific valvular involvement.

Cite This Study

Shrestha et al. (2012) studied this question.

synapsesocial.com/papers/6a7e2fa73376ac4793f7106ahttps://doi.org/10.2459/jcm.0b013e32835854b6

Topics

Mitral valve interventionValvular heart disease
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1High Prevalence of Rheumatic Heart Disease Detected by Echocardiography in School Children2010 · 112 citations
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  3. 3Group A Streptococcal Serotypes Isolated from Patients and Sibling Contacts During the Resurgence of Rheumatic Fever in the United States in the Mid-1980s1989 · 124 citations
  4. 4Acute rheumatic fever and rheumatic heart disease in the Top End of Australia's Northern Territory1996 · 222 citations