Key result
Feline HCM with left atrial enlargement is linked to ~46% worse LVGLS versus controls.
Why the study?
Early detection of myocardial dysfunction in cats with hypertrophic cardiomyopathy remains challenging using conventional echocardiography alone.
Does multi-chamber strain echocardiography improve the characterization of myocardial dysfunction in cats with hypertrophic cardiomyopathy phenotypes compared to conventional echocardiography?
Population
40 client-owned cats
Comparison
Healthy controls vs hypertrophic phenotype with normal LA vs hypertrophic phenotype with LA enlargement
Design
Retrospective observational study
Authors
Loading...
May aid early feline HCM detection beyond conventional echo; hypothesis-generating for prognostic validation.
Observational (n=40)
No
Does multi-chamber strain echocardiography improve the characterization of myocardial dysfunction in cats with hypertrophic cardiomyopathy phenotypes compared to conventional echocardiography?
Absolute Event Rate: -11.95% vs -22.09%
p-value: p=<0.0001
Strain-derived parameters, particularly LVGLS and LARS, provide complementary functional information beyond conventional echocardiography for detecting early myocardial dysfunction in feline hypertrophic cardiomyopathy.
Ying et al. (2026) conducted an observational in Hypertrophic cardiomyopathy (n=40). Hypertrophic cardiomyopathy with left atrial enlargement vs. Healthy controls was evaluated on Left ventricular global longitudinal strain (LVGLS) (p=<0.0001). Cats with hypertrophic cardiomyopathy and left atrial enlargement exhibited significantly lower left ventricular global longitudinal strain (-11.95% vs -22.09%, p<0.0001) compared to healthy controls.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: