Key result
Cats with hypertrophic cardiomyopathy had significantly lower peak atrial longitudinal strain compared to healthy controls (13.16 vs 28.54, P < 0.001), indicating reduced left atrial function.
Why the study?
Left atrial function plays an important role in diastolic dysfunction in cats with hypertrophic cardiomyopathy, and the study aimed to evaluate changes in LA function in HCM cats compared to normal cats using 2D-STE.
Does two-dimensional speckle tracking echocardiography (2D-STE) detect reduced left atrial function in cats with hypertrophic cardiomyopathy compared to healthy controls?
Comparison
Cats affected with HCM vs healthy control cats
Authors
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May indicate early left atrial dysfunction in feline HCM; hypothesis-generating for prognostic validation in prospective studies.
Case-Control (n=37)
No
Does two-dimensional speckle tracking echocardiography (2D-STE) detect reduced left atrial function in cats with hypertrophic cardiomyopathy compared to healthy controls?
Absolute Event Rate: 13.16% vs 28.54%
p-value: p=<0.001
Peak atrial longitudinal strain assessed by 2D-STE is a feasible and reproducible method that detects reduced left atrial function in cats with hypertrophic cardiomyopathy.
Kiatsilapanan et al. (2020) conducted a case-control in Feline hypertrophic cardiomyopathy (n=37). Hypertrophic cardiomyopathy vs. Healthy control cats was evaluated on Peak atrial longitudinal strain (PALS) (p=<0.001). Cats with hypertrophic cardiomyopathy had significantly lower peak atrial longitudinal strain compared to healthy controls (13.16 vs 28.54, P < 0.001), indicating reduced left atrial function.
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