Key result
Cats with hypertrophic cardiomyopathy had lower peak atrial longitudinal strain compared to healthy control cats, indicating reduced left atrial function.
Why the study?
Left atrial function plays an important role in diastolic dysfunction in cats with HCM, and this study aimed to evaluate LA function using 2D-STE compared to normal cats.
Does two-dimensional speckle tracking echocardiography detect reduced left atrial function in cats with hypertrophic cardiomyopathy compared to healthy controls?
Observational (n=37)
No
Does two-dimensional speckle tracking echocardiography detect reduced left atrial function in cats with hypertrophic cardiomyopathy compared to healthy controls?
Two-dimensional speckle tracking echocardiography is a feasible and reproducible method that demonstrates significantly reduced peak atrial longitudinal strain in cats with hypertrophic cardiomyopathy.
Answers are grounded in this paper and cite their sources.
Identifies reduced left atrial function in feline HCM; leaves open its value for prognosis or management.
Background : Left atrial (LA) function plays an important role in diastolic dysfunction in cats with hypertrophic cardiomyopathy (HCM). Two-dimensional speckle tracking echocardiography (2D-STE) is a technique for assessing LA function. This study aimed to evaluate the LA function in HCM cats compared to normal cats, using 2D-STE. Results: Seventeen client-owned cats affected with HCM and twenty healthy control cats were studied. Conventional echocardiographic and 2D-STE variables were measured and compared between groups (control and HCM groups). Variability of the peak atrial longitudinal strain (PALS) displayed good reproducibility with 4.7% intra-observer and 14% inter-observer repeatability. The mean value of PALS in the HCM group (13.16 ± 8.64) was lower than that in the control group (28.54 ±10.31) ( P < 0.001). PALS was lowest in the LA roof region. The atrial longitudinal strains of septal and lateral regions were significantly lower in the HCM group than in the normal group. The PALS correlated with the percentage of the LA fractional shortening (LA-FS) (r=0.538, P =0.001), the percentage of the LA ejection fraction (LA-EF) (r =0.797, P <0.001), and the LA fractional area change (FAC) (r =0.746, P <0.001). Conclusions: PALS is a feasible and reproducible method to evaluate the LA function in cats affected with HCM.
No takes yet. Share an insight, caveat, or question.
Kiatsilapanan et al. (2020) conducted an observational in Feline hypertrophic cardiomyopathy (n=37). Hypertrophic cardiomyopathy vs. Healthy control cats was evaluated on Peak atrial longitudinal strain (PALS) (p=<0.001). Cats with hypertrophic cardiomyopathy had lower peak atrial longitudinal strain compared to healthy control cats, indicating reduced left atrial function.
Synapse has enriched 8 closely related papers on similar clinical questions. Consider them for comparative context: