Right ventricle free wall mechanics in metabolic syndrome without type-2 diabetes: effects of a 3-month lifestyle intervention program

79 adults (39 with metabolic syndrome free of type-2 diabetes, 40 healthy age- and gender-matched controls). MetS group mean age 59.6, 51.2% female. Exclusions: cardiopathy, type-2 diabetes, sleep apnea, pulmonary diseases, pulmonary hypertension, and coronary artery disease.

3-month lifestyle intervention program including a 3-week residential program followed by home-based continuation. Included individualized diet (500 kcal/day deficit) and physical exercise (endurance and resistance training, 90 min, 4-5 days/week).

40 healthy age- and gender-matched controls with no cardiovascular risk factors (assessed at baseline only). The study also evaluated pre-post intervention changes within the MetS group.

Right ventricle (RV) free wall global longitudinal strain (GLS) and strain rates (SR) assessed by vector velocity imaging at 3 months.surrogate