Why the study?
The comparative effectiveness of specific antihypertensive agents in preventing new-onset or recurrent AF remains under debate.
Do specific antihypertensive agents reduce the risk of new-onset or recurrent atrial fibrillation in patients with hypertension, diabetes, or AF?
Comparison
ACE inhibitors, ARBs, CCBs, β-blockers, MRAs, TDs, and combinations compared across classes
Design
Bayesian random-effects network meta-analysis of randomized controlled trials
Authors
Loading...
ACEI, ARB, or β-blocker use may lower AF risk versus CCBs in hypertension; extends class-specific RCT evidence.
Do specific antihypertensive agents reduce the risk of new-onset or recurrent atrial fibrillation in patients with hypertension, diabetes, or AF?
In patients with hypertension, diabetes, or AF, ACE inhibitors (alone or with thiazide diuretics) and ARBs are more effective than CCBs in preventing new-onset or recurrent atrial fibrillation.
Gewehr et al. (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: