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January 12, 2012European Journal of Cardio-Thoracic SurgeryOpen Access

Initial experience with polytetrafluoroethylene leaflet extensions for aortic valve repair

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Why the study?

Does aortic valvuloplasty using PTFE leaflet extensions improve echocardiographic parameters in patients with congenital aortic valve disease?

Population

13 patients with congenital valvular disease, median age 14 years, median weight 58 kg.

Design

Case_series

Follow-up

mean 14.8 ± 9 months (range 2-30 months)

Authors

MNMarcin NosalRPRudolf PorubanPVPavel Valentík

Discussion

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Member takes

Overview

May support short-term hemodynamic benefit of PTFE extensions in congenital aortic valve disease; leaves open durability and generalizability.

Structured PICO

Does aortic valvuloplasty using PTFE leaflet extensions improve echocardiographic parameters in patients with congenital aortic valve disease?

P
Population
13 patients with congenital valvular disease (aortic stenosis and/or insufficiency), median age 14 years, median weight 58 kg.
I
Intervention
Aortic valvuloplasty using polytetrafluoroethylene (PTFE) leaflet extensions in a tri-leaflet configuration.
O
Outcome
Aortic insufficiency degree and mean gradient across the aortic valve at follow-up.surrogate

Aortic valve repair using PTFE leaflet extensions is an effective technique for improving hemodynamics in congenital valvular disease, though long-term durability remains to be established.

Limitations

  • Long-term follow-up is necessary to assess the durability of this type of repair

Cite This Study

Nosal et al. (2012) studied this question.

synapsesocial.com/papers/6a7e30dad2dab736758561b8https://doi.org/10.1093/ejcts/ezr214
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Polytetrafluoroethylene Bicuspid Pulmonary Valve Implantation: Experience With 126 Patients2010 · 60 citations
  2. 2Ten-Year Experience of Chordal Replacement With Expanded Polytetrafluoroethylene in Mitral Valve Repair2000 · 74 citations
  3. 3Aortic valve-sparing repair with autologous pericardial leaflet extension has a greater early re-operation rate in congenital versus acquired valve disease☆2006 · 25 citations
  4. 4Up to 16 years follow-up of aortic valve reconstruction with pericardium: a stentless readily available cheap valve?☆2005 · 185 citations
  5. 5Long-term results of conservative repair of rheumatic aortic valve insufficiency1988 · 69 citations