Why the study?
The Ind-2001 lineage of the foot-and-mouth disease virus has been implicated in outbreaks in Pakistan, prompting analysis of its evolutionary dynamics, geographical distribution, and VP1 protein.
Population
50 samples from Pakistan
Design
Evolutionary and phylogenetic analysis
Authors
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May signal FMD vaccine mismatch risk; leaves open cross-protection extent and need for updated strain surveillance.
The emergence of the novel O/ME-SA/Ind-2001e lineage of FMDV in Pakistan with VP1 epitope mutations suggests potential challenges to current vaccination efficacy.
Munir et al. (2023) studied this question.
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