Key result
Genetic characterization of 286 FMDV serotype O isolates in India (2014-2018) revealed dominance of sub-lineage O/ME-SA/Ind2001e and emergence of a novel O/ME-SA/2018 cluster.
Why the study?
Foot-and-mouth disease is endemic in India with dominant serotype O outbreaks, warranting an understanding of the distribution and antigenic behaviour of topotypes and lineages during 2014-2018.
Population
286 FMDV serotype O viral isolates in India
Design
Observational genetic and antigenic characterization study
Authors
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Emergence of Ind2001e and novel 2018 cluster warrants enhanced FMDV surveillance in India; leaves open long-term vaccine performance against evolving strains.
Observational (n=286)
The study identifies the emergence and dominance of the O/ME-SA/Ind2001e sub-lineage and a novel O/ME-SA/2018 cluster of FMDV in India, while confirming the Indian vaccine strain provides adequate antigenic coverage.
Dahiya et al. (2020) conducted an observational in Foot-and-mouth disease (n=286). FMDV serotype O lineages was evaluated on Distribution of topotype/lineages and antigenic behavior. Genetic characterization of 286 FMDV serotype O isolates in India (2014-2018) revealed dominance of sub-lineage O/ME-SA/Ind2001e and emergence of a novel O/ME-SA/2018 cluster.
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