August 23, 2023Journal of Clinical MedicineOpen Access

The median TWA of hypotension below 65 mmHg was significantly lower in the HPI group (0.070 mmHg, IQR 0.020-0.240) compared to the non-HPI group (0.180 mmHg, IQR 0.060-0.410) (p < 0.001).

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Why the study?

Intraoperative hypotension is common and associated with increased morbidity and mortality, but whether the Hypotension Prediction Index reduces hypotensive events in non-cardiac surgery patients remained to be tested.

Does the Hypotension Prediction Index reduce the incidence and duration of intraoperative hypotension in non-cardiac surgery patients?

Population

136 matched non-cardiac surgery patients selected from 769 patients

Comparison

HPI application vs non-HPI group

Design

Single-center propensity-score-matched study

Authors

JRJulian Runge JGJessica Graw CGCarla D. Grundmann

Discussion

Member takes

Overview

HPI use was associated with less hypotension; hypothesis-generating and requires RCTs before practice change.

Structured PICO

Does the Hypotension Prediction Index reduce the incidence and duration of intraoperative hypotension in non-cardiac surgery patients?

Population

136 propensity-score-matched non-cardiac surgery patients (selected from an initial cohort of 769 patients)

Intervention

Hypotension Prediction Index (HPI) guidance combined with a goal-directed treatment protocol

Comparator

Goal-directed treatment protocol without HPI guidance

Outcome

Incidence and duration of hypotensive events defined as MAP < 65 mmHg, evaluated by the time-weighted average (TWA) of hypotensionsurrogate

The use of the Hypotension Prediction Index during non-cardiac surgery significantly reduces the time-weighted average of intraoperative hypotension, particularly in higher-risk patients.

Cite This Study

Runge et al. (2023) studied this question.

synapsesocial.com/papers/6a7e45d2196d67da7483e2ca https://doi.org/10.3390/jcm12175479

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August 23, 2023Journal of Clinical MedicineOpen Access

The median TWA of hypotension below 65 mmHg was significantly lower in the HPI group (0.070 mmHg, IQR 0.020-0.240) compared to the non-HPI group (0.180 mmHg, IQR 0.060-0.410) (p < 0.001).

View Full Paper

Ask AI

Bookmark

Why the study?

Does the Hypotension Prediction Index reduce the incidence and duration of intraoperative hypotension in non-cardiac surgery patients?

Population

136 matched non-cardiac surgery patients selected from 769 patients

Comparison

HPI application vs non-HPI group

Design

Single-center propensity-score-matched study

Authors

JRJulian Runge JGJessica Graw CGCarla D. Grundmann

Discussion

Member takes

Overview

HPI use was associated with less hypotension; hypothesis-generating and requires RCTs before practice change.

Structured PICO

Does the Hypotension Prediction Index reduce the incidence and duration of intraoperative hypotension in non-cardiac surgery patients?

Population

136 propensity-score-matched non-cardiac surgery patients (selected from an initial cohort of 769 patients)

Intervention

Hypotension Prediction Index (HPI) guidance combined with a goal-directed treatment protocol

Comparator

Goal-directed treatment protocol without HPI guidance

Outcome

Incidence and duration of hypotensive events defined as MAP < 65 mmHg, evaluated by the time-weighted average (TWA) of hypotensionsurrogate

The use of the Hypotension Prediction Index during non-cardiac surgery significantly reduces the time-weighted average of intraoperative hypotension, particularly in higher-risk patients.

Cite This Study

Runge et al. (2023) studied this question.

synapsesocial.com/papers/6a7e45d2196d67da7483e2ca https://doi.org/10.3390/jcm12175479

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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