Why the study?
Does diabetes mellitus reduce cardiac sympathetic activity in patients with severe heart failure?
Population
89 patients, including 75 with severe heart failure and 14 diabetic patients with normal cardiac function.
Comparison
Diabetes mellitus vs Absence of diabetes mellitus
Design
Cross-sectional
Authors
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DM may worsen sympathetic denervation in severe HF; hypothesis-generating and should not yet change practice.
Does diabetes mellitus reduce cardiac sympathetic activity in patients with severe heart failure?
Diabetes mellitus is associated with a greater reduction in cardiac sympathetic activity in patients with severe heart failure, with the degree of impairment correlating with HbA1c levels.
Paolillo et al. (2013) studied this question.
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