Why the study?
This pilot study was conducted to analyze changes in body composition, cardiorespiratory fitness, biochemical profile, clinical symptoms, and quality of life in adults with resistant major depression following combined exercise training.
Does 12 weeks of combined exercise training improve clinical symptoms, quality of life, and cardiorespiratory fitness in adults with resistant major depression?
Comparison
12 weeks of supervised combined exercise training
Design
Pilot study
Follow-up
12 weeks
Authors
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May support exercise for resistant depression symptoms and QoL; hypothesis-generating and requires RCTs to confirm.
Does 12 weeks of combined exercise training improve clinical symptoms, quality of life, and cardiorespiratory fitness in adults with resistant major depression?
A 12-week supervised combined exercise program improves clinical symptoms and quality of life in adults with resistant major depression, despite no significant changes in cardiorespiratory fitness or body composition.
Tous‐Espelosin et al. (2025) studied this question.
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