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October 31, 2002StrokeOpen Access

Bilateral Symmetry of Human Carotid Artery Atherosclerosis

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Why the study?

Is atherosclerosis of the human carotid arteries bilaterally symmetrical in terms of wall volume and calcification?

Population

50 pairs of carotid arteries from cadaveric donors, of which 38 pairs met criteria for rigorous analysis.

Comparison

MRI and electron-beam CT imaging of the carotid… vs Left versus right carotid arteries

Design

Cross-sectional

Authors

GAGareth AdamsBaylor College of MedicineDSDarlene M. SimoniBaylor College of MedicineCBCassius BordelonBaylor College of Medicine

Discussion

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Implication

Supports bilateral symmetry in carotid atherosclerosis; leaves open whether unilateral imaging suffices for contralateral assessment.

Structured PICO

Is atherosclerosis of the human carotid arteries bilaterally symmetrical in terms of wall volume and calcification?

P
Population
50 pairs of carotid arteries from cadaveric donors (aged 48 to 98 years), of which 38 pairs met criteria for rigorous analysis.
I
Intervention
MRI and electron-beam CT imaging of the carotid arteries
C
Comparator
Left versus right carotid arteries
O
Outcome
Similarity of atherosclerotic plaques (total wall volume measured by MRI and calcification scores measured by electron-beam CT) between left and right carotid arteriessurrogate

Atherosclerosis of the human carotid arteries is generally a bilaterally symmetrical disease, suggesting diagnostic information from one side can infer composition and volume on the contralateral side.

Cite This Study

Adams et al. (2002) studied this question.

synapsesocial.com/papers/6a7e58d6d2dab736758567bchttps://doi.org/10.1161/01.str.0000035736.30488.7a
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Also Consider

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