April 1, 2000Acta Physiologica Scandinavica

Anaplerosis of the citric acid cycle: role in energy metabolism of heart and skeletal muscle

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Population

Heart and skeletal muscle

Design

Review

Authors

MGMartin J. GibalaNatural Sciences and Engineering Research Council MYMartin E. YoungGeneral Cardiology HTH. TaegtmeyerThe University of Texas Health Science Center at Houston

Discussion

Member takes

Implication

Undetermined obligatory role for anaplerosis in exercise; leaves open its contribution to cardiac and skeletal muscle function.

Structured PICO

Population

Heart and skeletal muscle

Intervention

Anaplerosis of the citric acid cycle (TCA cycle)

Outcome

Energy metabolism and contractile functionsurrogate

This review highlights the presence and potential regulatory role of anaplerotic pathways in maintaining TCA cycle intermediates and contractile function in heart and skeletal muscle during exercise.

Cite This Study

Gibala et al. (2000) studied this question.

synapsesocial.com/papers/6a7e598f2fd85368b24d8f8a https://doi.org/10.1046/j.1365-201x.2000.00717.x

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Bookmark

Anaplerosis of the citric acid cycle: role in energy metabolism of heart and skeletal muscle

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Anaplerosis of the citric acid cycle: role in energy metabolism of heart and skeletal muscle

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider