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Four mechanisms are suggested to cover all types of emphysema: hypoplasia, atrophy, overinflation and destruction. Three anatomic types are described, each with a characteristic distribution: centriacinar, panacinar, and periacinar or paraseptal. A classification is presented in which obstruction of the airways (the key disturbance in lung function) is the main basis of subdivision.
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Lynne Reid (1966) studied this question.
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