Perfusion and Contractile Reserve in Chronic Dysfunctional Myocardium: Relation to Functional Outcome After Surgical Revascularization
Why the study?
Does the presence of intact perfusion and/or contractile reserve predict functional recovery after surgical revascularization in patients with ischemic cardiomyopathy?
Population
114 patients with ischemic cardiomyopathy undergoing surgical revascularization
Design
Cohort
Follow-up
9 to 12 months
Authors
Discussion
Loading...
Member takes
Implication
Supports viability assessment combining perfusion and contractile reserve in ischemic cardiomyopathy; hypothesis-generating and requires prospective validation before guiding revascularization.
Structured PICO
Does the presence of intact perfusion and/or contractile reserve predict functional recovery after surgical revascularization in patients with ischemic cardiomyopathy?
P
Population
114 patients with ischemic cardiomyopathy undergoing surgical revascularization
I
Intervention
Preoperative assessment of perfusion using resting (99m)Tc tetrofosmin and contractile reserve using low-dose dobutamine echocardiography
O
Outcome
Recovery of contractile function assessed by two-dimensional echocardiography at 9 to 12 months after revascularizationsurrogate
In patients with ischemic cardiomyopathy, segments with both intact perfusion and contractile reserve have a high likelihood of functional recovery post-revascularization, whereas those with intact perfusion alone have an intermediate likelihood.
Cite This Study
Bax et al. (2002) studied this question.