Unclassifiable B-cell lymphoma with features intermediate between diffuse large B-cell lymphoma and classical Hodgkin lymphoma in an AIDS patient. Report of a case and literature review

B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma (DLBCL) and classic Hodgkin lymphoma (cHL) is a B-celltype of lymphoma that demonstrates clinical, morphological, and/or immunophenotypic features between cHL and DLBCL. These lymphomas are most commonly associated with mediastinal disease, but some cases have been reported in peripheral lymph node as the primary site. This category was designed as a way to include those borderline cases that cannot be classified into a single distinct disease. Typically, these cases have features intermediate between DLBCL and cHL, or include characteristics of both lymphomas. Generally, immunophenotype showed CD20 weak or variably positive, CD15 expressed, CD30+, CD45+, CD79a+, OCT2 positive, BOB1 expressed and PAX5 positive expressed in atypical lymphoid cells. Here we present a female patient with AIDS who developed an unclassified lymphoma, with features between DLBCL and cHL.