Population
19 Cavalier King Charles Spaniels (CKCS) with mitral valve prolapse (MVP) and 7 control dogs (not CKCS)
Comparison
Cavalier King Charles Spaniels with mitral valve… vs Control dogs (not CKCS)
Design
Preclinical
Authors
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Does not support changes in canine platelet management; hypothesis-generating for magnesium and size effects in CKCS mitral valve models.
In a canine model of mitral valve prolapse, dogs with normal platelet counts exhibited increased platelet aggregation, whereas those with thrombocytopenia had normal aggregation but enlarged platelets and hypomagnesemia.
Olsen et al. (2001) studied this question.
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