Why the study?
Does the PFA-100 detect decreased platelet function in Cavalier King Charles Spaniels with mitral valve regurgitation?
Population
101 clinically healthy dogs > 1 year of age, including 15 control dogs of different breeds and 86 Cavalier…
Comparison
Platelet Function Analyzer (PFA-100) testing vs Control dogs of different breeds and CKCS with…
Design
Preclinical
Authors
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May support PFA-100 detection of platelet dysfunction in CKCS with MR; leaves open clinical relevance and need for prospective validation.
Does the PFA-100 detect decreased platelet function in Cavalier King Charles Spaniels with mitral valve regurgitation?
Cavalier King Charles Spaniels with clinically inapparent mitral regurgitation have decreased platelet function as measured by the PFA-100 device.
Tarnow et al. (2003) studied this question.
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