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October 6, 2008European Journal of Heart FailureOpen Access

Left aTrial Velocity Vector Imaging for the Detection and Quantification of Left Ventricular Diastolic Function in Type 2 Diabetes

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Why the study?

Does left atrial strain measured by velocity vector imaging accurately detect left ventricular diastolic dysfunction in patients with type 2 diabetes?

Population

87 patients with type 2 diabetes mellitus, mean age 60+/-7 years, 49% male, classified as having no, mild or…

Comparison

Velocity vector imaging to evaluate left atrial… vs Doppler echocardiography and Tissue Doppler…

Design

Cross-sectional

Authors

CJChristina JarnertAMA. MelcherKCKenneth Caidahl

Discussion

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Overview

LA roof strain shows limited accuracy for diastolic dysfunction in T2D; leaves open its diagnostic utility pending prospective validation.

Structured PICO

Does left atrial strain measured by velocity vector imaging accurately detect left ventricular diastolic dysfunction in patients with type 2 diabetes?

P
Population
87 patients with type 2 diabetes mellitus, mean age 60+/-7 years, 49% male, classified as having no (n=60), mild (n=13) or moderate (n=14) left ventricular diastolic dysfunction.
I
Intervention
Velocity vector imaging (VVI) to evaluate left atrial (LA) deformation (strain) and volumes
C
Comparator
Doppler echocardiography (DE) and Tissue Doppler imaging (TDI)
O
Outcome
Detection and quantification of left ventricular diastolic dysfunctionsurrogate

While left atrial strain measured by velocity vector imaging is impaired in diabetic patients with diastolic dysfunction, it has limited discriminative power for detecting early diastolic dysfunction.

Limitations

  • VVI has too limited discriminative power to detect early LV diastolic dysfunction

Cite This Study

Jarnert et al. (2008) studied this question.

synapsesocial.com/papers/6a7e7c78f6941e90164c4e86https://doi.org/10.1016/j.ejheart.2008.08.012
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Feasibility of strain and strain rate imaging for the assessment of regional left atrial deformation: A study in normal subjects2005 · 205 citations
  2. 2Doppler Tissue Imaging: A Noninvasive Technique for Evaluation of Left Ventricular Relaxation and Estimation of Filling Pressures1997 · 3,038 citations
  3. 3How to diagnose diastolic heart failure: a consensus statement on the diagnosis of heart failure with normal left ventricular ejection fraction by the Heart Failure and Echocardiography Associations of the European Society of Cardiology2007 · 2,684 citations
  4. 4Estimation of left ventricular filling pressures using two-dimensional and Doppler echocardiography in adult patients with cardiac disease1993 · 780 citations
  5. 5How to diagnose diastolic heart failure a consensus statement2007 · 70 citations