Unreliable Estimation of Aortic Pulse Wave Velocity Provided by the Mobil‐O‐Graph Algorithm‐Based System in Marfan Syndrome

Figures

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  Figure 1. Distribution of systolic (red diamonds) and diastolic (green diamonds) blood pressure values according to age in patients with Marfan syndrome enrolled in the study.

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  Figure 2. Relationship between aortic pulse wave velocity (PWV), estimated by the Mobil‐O‐Graph, and measured carotid‐femoral PWV (cf‐PWV). On the left, the scatterplot shows linear correlation between cf‐PWV measured by arterial tonometry (PulsePen device), the noninvasive reference method, and PWV estimated by the Mobil‐O‐Graph. A linear regression line (red solid line) and the identity line (black dashed line) are also shown. On the right, the Bland‐Altman plot shows differences observed between measurements to the average values. Red solid line shows the mean values of differences, and red dashed lines show ±1.96×SD of differences.

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  Figure 3. Distribution of aortic pulse wave velocity (PWV) values related to age (left panels) and systolic blood pressure (right panels) in different methodological approaches. Blue dots represent carotid‐femoral PWV values measured by PulsePen tonometer. Yellow squares with red border represent aortic PWV values estimated by the Mobil‐O‐Graph. Dashed lines show the relationship between age and PWV (exponential regression analysis) and between systolic blood pressure and PWV (linear regression analysis).

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  Figure 4. Distribution of aortic pulse wave velocity (PWV) values related to age (left panels) and systolic blood pressure (right panels) in different methodological approaches. Blue dots represent carotid‐femoral PWV values measured by PulsePen tonometer. Yellow triangles with red border represent aortic PWV values estimated (e1 PWV in A and e2 PWV in B) using equations derived by the Reference Values for Arterial Stiffness Collaboration.20 Dashed lines show the relationship between age and PWV (exponential regression analysis) and between systolic blood pressure and PWV (linear regression analysis).

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  Figure 5. Factors affecting aortic pulse wave velocity (PWV) estimated by Mobil‐O‐Graph. Aortic PWV, estimated by the Mobil‐O‐Graph, is strongly associated (r 2=0.98) with age2 and brachial systolic blood pressure (SBP).