Why the study?
Heart failure management guided by an implantable pulmonary artery pressure sensor improves symptoms and reduces hospitalizations, prompting a review of pulmonary vascular physiology, recent data, and practical management guidelines.
Does management guided by an implantable pulmonary artery pressure sensor reduce heart failure hospitalizations and improve symptoms in patients with heart failure?
Does management guided by an implantable pulmonary artery pressure sensor reduce heart failure hospitalizations and improve symptoms in patients with heart failure?
Implantable pulmonary artery pressure sensors provide a promising remote monitoring platform that can improve symptoms and reduce hospitalizations in chronic heart failure.
PAP-guided management warrants use in selected NYHA III HF; confirms CHAMPION and extends benefit to real-world practice.
Purpose of Review Heart failure (HF) management guided by hemodynamics obtained from an implantable pulmonary artery pressure (PAP) sensor (CardioMEMS) improves symptoms and reduces HF hospitalizations (HFH). This paper reviews the theoretical basis of pulmonary vascular physiology, summarizes recently published data about CardioMEMS, and provides practical guidelines for patient selection and management. Recent Findings Compared to patients managed by standard care, HF patients randomized to PAP-guided treatment have a higher frequency of medication adjustments, resulting in lower PAP and fewer HFH. Real-world analyses further support associations between implant of the CardioMEMS sensor with reductions in PAP, hospitalizations, and mortality. Summary Implantable, wireless hemodynamic sensor technology is a promising remote monitoring platform for chronic HF. A phased approach using a treatment algorithm may improve the efficiency and effectiveness of pressure-guided therapy.
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Abraham et al. (2020) studied this question.
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