Why the study?
Does torasemide improve cardiac sympathetic nerve activity and left ventricular remodeling compared to furosemide in patients with non-ischaemic congestive heart failure?
Population
40 patients with non-ischaemic congestive heart failure (LVEF < 45%)
Comparison
Torasemide 4-8 mg/day added to… vs Furosemide 20-40 mg/day added to…
Design
RCT, randomly assigned
Follow-up
6 months
Authors
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Supports torasemide over furosemide in non-ischemic HF; extends RCT evidence on loop diuretic selection to sympathetic and remodeling endpoints.
Does torasemide improve cardiac sympathetic nerve activity and left ventricular remodeling compared to furosemide in patients with non-ischaemic congestive heart failure?
Torasemide, but not furosemide, improves cardiac sympathetic nerve activity and left ventricular remodeling in patients with non-ischemic heart failure.
Shu Kasama (2006) studied this question.
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