Interstitial lung disease associated with systemic-onset juvenile idiopathic arthritis

Álvaro Villarejo Pérez; Eugenia Enríquez Merayo; Carmen Gallego Herrero; Jaime de Inocencio Arocena

doi:10.1016/j.anpede.2026.504290

July 1, 2026Anales de Pediatría (English Edition)Open Access

Interstitial lung disease associated with systemic-onset juvenile idiopathic arthritis

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Key Points

To examine the presentation, clinical characteristics, and emergence of interstitial lung disease as a severe complication in systemic-onset juvenile idiopathic arthritis.
Reviewed clinical courses and respiratory manifestations in pediatric patients diagnosed with systemic-onset juvenile idiopathic arthritis.
Evaluated the relationship between underlying systemic inflammatory activity, biologic therapies, and the onset of pulmonary parenchymal involvement.
Identifies interstitial lung disease as an increasingly recognized and life-threatening extra-articular complication in systemic juvenile idiopathic arthritis.
Demonstrates atypical histopathological patterns, such as alveolar proteinosis and lipoid pneumonia, frequently co-occurring with episodes of macrophage activation syndrome.

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Implication

Clinical review demonstrates interstitial lung disease features in systemic juvenile idiopathic arthritis, highlighting emergent pulmonary complications.

Abstract

Interstitial lung disease associated with systemic

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Cite This Study

Pérez et al. (2026) studied this question.

synapsesocial.com/papers/6a7e9de0b06e944a47339093 https://doi.org/10.1016/j.anpede.2026.504290

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Interstitial lung disease associated with systemic-onset juvenile idiopathic arthritis

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

Interstitial lung disease associated with systemic-onset juvenile idiopathic arthritis

Key Points

No abstract yet

Implication

Abstract

Discussion

Cite This Study

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