Why the study?
Does temporary versus permanent coronary occlusion affect the inducibility of protracted ventricular tachycardia by premature stimuli in a canine model?
Population
28 dogs with infarcts subjected to either permanent occlusion of the left anterior descending coronary…
Comparison
Premature ventricular stimuli applied on the T… vs Permanent coronary occlusion versus temporary…
Design
Preclinical
Follow-up
2-9 days after surgery
Authors
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Reperfusion after temporary occlusion may promote VT substrate in this canine model; leaves open relevance to human post-MI arrhythmias.
Does temporary versus permanent coronary occlusion affect the inducibility of protracted ventricular tachycardia by premature stimuli in a canine model?
Temporary coronary occlusion with reperfusion creates a substrate of viable myocardium within necrotic regions that facilitates the induction of protracted ventricular tachycardia by premature stimuli.
Karagueuzian et al. (1979) studied this question.
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