Why the study?
What are the electrophysiologic changes before the onset of ventricular tachyarrhythmias during partial reperfusion following severe myocardial ischemia in dogs?
Population
26 dogs with severe myocardial ischemia induced by left anterior descending coronary artery occlusion and…
Design
Preclinical
Follow-up
Within 2 min of partial reperfusion
Authors
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May distinguish VT subtypes in canine reperfusion models; leaves open human translation.
What are the electrophysiologic changes before the onset of ventricular tachyarrhythmias during partial reperfusion following severe myocardial ischemia in dogs?
Slight improvement in fractionation induces sustained VT, whereas new deflections with large amplitude induce non-sustained VT degenerating to ventricular fibrillation during partial reperfusion in dogs.
Kuriyama et al. (1992) studied this question.
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