What question did this study set out to answer?

To assess whether gamma globulin derived from large pools of adult human serum can prevent or attenuate infectious hepatitis during epidemic outbreaks.

January 20, 1945JAMA

The Prevention and Attenuation of Infectious Hepatitis by Gamma Globulin

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Authors

JSJoseph StokesDublin City University

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Implication

Preliminary report demonstrates infectious hepatitis attenuation using pooled gamma globulin in human populations, suggesting an effective method for epidemic control.

Key Points

To assess whether gamma globulin derived from large pools of adult human serum can prevent or attenuate infectious hepatitis during epidemic outbreaks.
Evaluated the preventive and therapeutic administration of gamma globulin concentrated from large pools of adult human serum.
Assessed historical clinical risks related to parenteral injections of homologous blood products, such as whole blood and convalescent plasma, from small donor pools.
Administration of pooled adult human gamma globulin demonstrated potential efficacy in controlling and mitigating infectious hepatitis epidemics.
Parenteral administration of blood products from single donors or small pools was noted to carry documented risks of transmitting hepatitis.

Cite This Study

Joseph Stokes (1945) studied this question.

synapsesocial.com/papers/6a7eae3ababc2b64f88b9ba5 https://doi.org/10.1001/jama.1945.02860030016004

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Implication

Preliminary report demonstrates infectious hepatitis attenuation using pooled gamma globulin in human populations, suggesting an effective method for epidemic control.

The Prevention and Attenuation of Infectious Hepatitis by Gamma Globulin

Discussion

Member takes

Implication

Key Points

Cite This Study

The Prevention and Attenuation of Infectious Hepatitis by Gamma Globulin

Discussion

Member takes

Implication

Key Points

Cite This Study

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