Population
Normal and pathological kidneys (including renal tumours and developing kidneys in all species studied)
Design
Review
Authors
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Refines intrarenal RAS models; leaves open effects on RAS inhibitor efficacy in hypertension or HF.
This review clarifies the anatomical localization of the renin-angiotensin system in the kidney, suggesting renin is primarily secreted into the interstitium rather than the vessel lumen.
Lindop et al. (1986) studied this question.
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