Population
Patients with hypertension and congestive heart failure
Design
Review
Authors
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May support preferring AT1-receptor blockers for tolerability in hypertension and HF; leaves open confirmation via head-to-head RCTs.
AT1-receptor blockers like losartan offer similar efficacy to ACE inhibitors for hypertension and heart failure but with a more favorable adverse effect profile.
Gordon P. Guthrie (1995) studied this question.
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