Why the study?
Although amphetamine use is traditionally linked to haemorrhagic stroke, up to one-third of stimulant-associated cardiomyopathy patients develop left ventricular thrombus, increasing systemic embolization risk.
Sustained amphetamine use can cause severe dilated cardiomyopathy with left ventricular thrombus and embolic stroke, requiring prompt intervention and guideline-directed medical therapy.
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Screen amphetamine cardiomyopathy patients for LV thrombus to prevent embolic events; challenges traditional hemorrhagic-stroke association and leaves open optimal anticoagulation.
Chapman et al. (2022) studied this question.
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