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August 14, 2026BMC Health Services ResearchOpen Access

Outcomes of evidence-based psychotherapy for healthcare workers: a single-arm prospective cohort study

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Authors

JMJon MorgensternSLSvetlana LevakSMSean P. Madden

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Overview

Prospective cohort study reveals substantial reductions in depression and anxiety in healthcare workers, indicating that scalable digital psychotherapy effectively expands mental health access.

Key Points

  • To evaluate treatment engagement and clinical outcomes of an employer-sponsored digital psychotherapy program for healthcare workers and their adult dependents.
  • Conducted a single-arm prospective cohort study from March 2022 through July 2024 within a large integrated healthcare system.
  • Enrolled N=496 adults (employees or dependents; 348 completed at least one follow-up) with baseline PHQ-9 or GAD-7 scores ≥5 who received weekly evidence-based digital psychotherapy.
  • Mean symptom scores decreased significantly from baseline by 6.4 points on the PHQ-9 (95% CI, 5.7 to 7.1; p < 0.001; d ≈ 1.3) and 6.3 points on the GAD-7 (95% CI, 5.8 to 6.9; p < 0.001; d ≈ 1.3).
  • Among participants with baseline clinical elevation (score ≥10), 36.5% achieved depression remission and 48.8% achieved anxiety remission (score <5).
  • Participants attended a mean of 15 therapy sessions, achieved an 81.9% completion rate, and treatment completion was significantly associated with greater symptom improvement.

Cite This Study

Morgenstern et al. (2026) studied this question.

synapsesocial.com/papers/6a7ec6c6b70b84ec8b912e7dhttps://doi.org/10.1186/s12913-026-15301-8
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