Why the study?
Does glyburide improve glycemic control compared to insulin in women with gestational diabetes mellitus?
Population
404 women with singleton pregnancies and gestational diabetes requiring treatment, randomized between 11 and…
Comparison
Glyburide according to an intensified treatment… vs Insulin according to an intensified treatment…
Design
RCT, Randomly assigned between 11 and 33 weeks of gestation
Authors
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Glyburide matches insulin for glycemic control without excess neonatal complications; supports its use as an oral alternative in gestational diabetes.
Does glyburide improve glycemic control compared to insulin in women with gestational diabetes mellitus?
In women with gestational diabetes, glyburide is a clinically effective alternative to insulin therapy for achieving glycemic control without increasing neonatal complications.
Langer et al. (2000) studied this question.
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