June 11, 2011Circulation Arrhythmia and Electrophysiology
Ablation of Ventricular Arrhythmias in Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy
Why the study?
Does endo-epicardial ablation improve long-term freedom from recurrent ventricular arrhythmias compared to endocardial-alone ablation in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy?
Population
49 patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy undergoing ablation of…
Comparison
Endo-epicardial substrate-based ablation (n=26). vs Endocardial-alone ablation (n=23).
Design
Cohort
Follow-up
at least 3 years
Authors
Discussion
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Member takes
Implication
Endo-epicardial ablation was associated with higher arrhythmia-free survival in ARVD/C; leaves open whether randomized trials should confirm this observational finding.
Structured PICO
Does endo-epicardial ablation improve long-term freedom from recurrent ventricular arrhythmias compared to endocardial-alone ablation in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy?
P
Population
49 patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) undergoing ablation of ventricular tachycardia (VT), all with an implantable cardioverter-defibrillator (ICD).
I
Intervention
Endo-epicardial substrate-based ablation (n=26).
C
Comparator
Endocardial-alone ablation (n=23).
O
Outcome
Long-term freedom from recurrent ventricular arrhythmias (VAs) or ICD therapy after at least 3 years of follow-up.hard clinical
An endo-epicardial ablation strategy significantly improves long-term freedom from recurrent ventricular arrhythmias and reduces the need for antiarrhythmic drugs compared to endocardial-alone ablation in patients with ARVD/C.
Cite This Study
Bai et al. (2011) studied this question.