Why the study?
Does an extracellular matrix (ECM) scaffold support myocardial repair and constructive remodeling in animal models with right ventricular defects?
Does an extracellular matrix (ECM) scaffold support myocardial repair and constructive remodeling in animal models with right ventricular defects?
Porcine extracellular matrix scaffolds can alter typical scar tissue healing in myocardial defects, supporting vascularization and the development of contractile myocardium in animal models.
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Supports functional remodeling in animal RV defects; leaves open translation to human myocardial repair.
Badylak et al. (2005) studied this question.
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