Population
Rat soleus muscles
Design
Preclinical
Follow-up
14 days
Authors
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Highlights early gene shifts in rat atrophy; hypothesis-generating for disuse mechanisms and should not yet inform practice.
The study identified temporal patterns of gene expression underlying muscle atrophy during hindlimb unloading in rats, highlighting early activation of regulatory and ubiquitination genes.
Stevenson et al. (2003) studied this question.
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