A donor-dependent fraction of human Lp(a) lacks lysine-binding capability, failing to inhibit plasminogen activation or bind fibrinogen, which highlights functional heterogeneity that may affect its atherothrombotic risk profile.
No takes yet. Share an insight, caveat, or question.
Lp(a) functional heterogeneity may modulate atherothrombotic risk; leaves open isoform-specific effects on human cardiovascular outcomes.
Leerink et al. (1992) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: