Why the study?
Does fentanyl alter heart rate variability during spontaneous and paced breathing in healthy volunteers?
Does fentanyl alter heart rate variability during spontaneous and paced breathing in healthy volunteers?
Low-dose fentanyl decreases sympathetic and overall autonomic nervous system modulation in healthy volunteers, with a trend toward vagal activation.
No takes yet. Share an insight, caveat, or question.
Should not yet change perioperative opioid use; leaves open clinical relevance of fentanyl's autonomic effects in patients.
Vettorello et al. (2008) studied this question.