Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
May 7, 2012Colorectal Disease

Anastomotic leakage occurred in 6.4% of patients, with laparoscopic surgery (OR 1.34, 95% CI 1.05-1.70, P=0.03) and blood transfusion (OR 10.27, 95% CI 6.82-15.45, P<0.001) independently associated with increased risk.

View Full Paper
Ask AI
Bookmark
Share

Why the study?

What are the risk factors associated with anastomotic leakage in patients undergoing curative colonic cancer surgery?

Population

9,333 patients subjected to curative colonic cancer surgery with primary anastomosis entered into The Danish…

Design

Cohort

Authors

PKPeter‐Martin KrarupLJLars Nannestad JørgensenAAAnne Helms Andreasen

Discussion

Loading...

Member takes

Overview

May support risk stratification for anastomotic leak after colonic resection; leaves open whether these factors are causal or modifiable.

Structured PICO

What are the risk factors associated with anastomotic leakage in patients undergoing curative colonic cancer surgery?

P
Population
9,333 patients subjected to curative colonic cancer surgery with primary anastomosis entered into The Danish Colorectal Cancer Group database between May 2001 and December 2008
I
Intervention
Risk factor analysis (including laparoscopic surgery, left hemicolectomy, sigmoid colectomy, intra-operative blood loss, blood transfusion, male gender)
O
Outcome
Anastomotic leakage (AL)safety

Laparoscopic surgery and blood transfusions are significant risk factors for anastomotic leakage following curative colonic cancer surgery.

Cite This Study

Krarup et al. (2012) studied this question.

synapsesocial.com/papers/6a7ee3810d396ca0cf0fba05https://doi.org/10.1111/j.1463-1318.2012.03079.x
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Anastomotic Leak in Colorectal Surgery: Predictive Factors and Survival2022 · 3 citations
  2. 2Risk Factors for Sigmoid Colonic Anastomosis: A Comparative and Cross-Sectional Analysis2025 · 2 citations
  3. 3Risk factors associated with anastomotic leakage in patients operated due to colorectal tumour2019 · 5 citations
  4. 4Emergency Surgery and the Risk of Anastomotic Leakage After Colorectal Resection with Primary Anastomosis for Benign and Malignant Disease: A Single-Center Retrospective Study2026
  5. 5Anastomotic Leakage in Emergency Colorectal Surgery: Clinical Features and Associated Variables2026