Key result
Morphological characteristics of intracoronary thrombi, specifically old thrombi, layered structure, microchannels, peripheral inflammatory infiltrate, and white thrombi, significantly predicted the probability of achieving adequate TIMI 3 blood flow after primary PCI.
Why the study?
The study investigated the relationship between morphological characteristics of intracoronary thrombi and the probability of achieving adequate blood flow in the infarct-related coronary artery after primary PCI for STEMI.
Do morphological characteristics of intracoronary thrombi predict the probability of achieving adequate blood flow in the infarct-related coronary artery in patients with STEMI after primary PCI?
Observational (n=98)
Yes
Do morphological characteristics of intracoronary thrombi predict the probability of achieving adequate blood flow in the infarct-related coronary artery in patients with STEMI after primary PCI?
The morphological structure of intracoronary thrombi, specifically the presence of old thrombi, layered structure, microchannels, peripheral inflammatory infiltrate, and white thrombi, is significantly associated with the probability of achieving adequate TIMI 3 blood flow after primary PCI in STEMI patients.
Summary. Purpose. To study the relationship between the morphological characteristics of intracoronary thrombi and the probability of achieving adequate blood flow in the infarctrelated coronary artery in patients with ST-segment elevation acute myocardial infarction (STEMI) after primary percutaneous coronary intervention (PCI). Materials and methods. The analysis included 98 patients with STEMI who, in the first 12 hours from the onset of symptoms, underwent PCI and received thrombotic masses during manual thromboaspiration. The latter was analyzed macroand microscopically. Using the method of logistic regression with progressive selection, characteristics of thrombi affecting the probability of achieving adequate blood flow were identified. Results. From the set of factors investigated in the course of performing the work using the logistic regression method, 5 factors were separated that, when combined, have an impact on the probability of reaching TIMI 3 blood flow after PCI: old thrombi, layered structure, microchannels, inflammatory infiltrate on the periphery, and white thrombi Conclusions. The structure of the intracoronary thrombus has a significant connection with the probability of achieving adequate blood flow through the infarctrelated coronary artery.
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Беш et al. (2023) conducted an observational in ST-segment elevation acute myocardial infarction (STEMI) (n=98). Morphological characteristics of intracoronary thrombi vs. Absence of specific morphological characteristics was evaluated on Achievement of adequate blood flow (TIMI 3) in the infarct-related coronary artery after PCI (p=<0.0001). Morphological characteristics of intracoronary thrombi, specifically old thrombi, layered structure, microchannels, peripheral inflammatory infiltrate, and white thrombi, significantly predicted the probability of achieving adequate TIMI 3 blood flow after primary PCI.
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